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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789f520f7f869a29b18ee9868f047a4dd8c62c8c76e60d4ec42f898c2c54e6ab' 
  AND token = '0CeFlAEuJxxHRUZ2JIBqpib5bvyiJKPyCccqXRlEUOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}