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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c495ca5a5a137a536a82e9894117623b81c6ad26a52b091dbddd4725dd7505e5' 
  AND token = 'F8ivwQ423OxsaKR9b/CtRl0MsO2wTrfFex6r6CGH0KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}