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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac390aed5d23b593d9cc8aa2a9d501167e06f91433fde2a93ccdd3c6d4722cee' 
  AND token = 'fmowjmIlqUUYEvM58TmjSxql6903Z3Ij2/LMen61RnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}