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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c94120ecabc032c1da6200e06f24ef460bd37cad4dde125e7abafb8a5c61437' 
  AND token = 'Ewt/Vydl066KjcPy8A1zVqw9dCDrPgWZ1QOME+C7bE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}