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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc72ffc41598aed8672dea93284a26b548d3a7fca0397c5432f4e69d7a0d0c69' 
  AND token = 'rASNgaNTeBiZioEoUiXbz5xYrQ+uHeU6qTFN/ol4PCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}