SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df33fb41c8ca960de357c64cde5f93408cfd8b8f2142c4b17f289b5e7f464d00' 
  AND token = 'WTg3x4GRYPskW9OpeXhgKCaZPt7L2aj+r+eCxHJIE9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}