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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c45e0723c8350dbc236b184fa2538a008936d62fc28c1f6ff9c733fc2717908' 
  AND token = 'YqdZtCygukkZe0Qmlu9G+tyaLXZ0MdXrGYq48tk60xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}