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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246775160c485267ad24a9f7e426ae15a2eee0865f4061f40ad09b830941478e' 
  AND token = 'PcbvOS1U5l9JMB8Cek+kDqYFoIuooNvyPAAzeFL9osE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}