SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85a075832c5d3f7e35433237f16313c80c60885c61e501e025e19490874f16c7' 
  AND token = 'fYSrPic/IiMgeudsd4VNpvb15E9CMybAAjvwOoh2ISA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}