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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df02854836c6d379bcc2df16e7c3e70dc612812f8f2b224510d0cc3e349d1520' 
  AND token = 'IAE1ZyVdTB73meN3QrkyxeH7fxIwSfppMH53uYzCnh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}