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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d12e2066aba5bec624f3cf8862a9041d4649cd3c03e8e663c7550aeae4054dd' 
  AND token = 'vn4sFS+1nlC9P5WavZs7WFrZJBhDK5rA40E3g3Pgc2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}