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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b44180971fef7908d1bdae78c88ed6fff15dc39cedebccdb522ccb9e39a79e' 
  AND token = 'SVc+k1gn7vB9F1NpKA/yR+V37L5zygxbdl4SHcYEyj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}