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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d4708a813a6c1d9de753a25d58429d4007f06305de91ee9606745bf965f837' 
  AND token = 'knnV4f0t+FmsPZc4MGSF7DzMH9DDxNtYDdn0rm5SmpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}