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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8acf283d26ce6be933a3039ef7da7360ff0d0ef4b5b599465493bb1d39ebd0c1' 
  AND token = 'cbywHgHUfPvyD73NRGwaLfaZ9RAd6aRjCPKGHqp1cP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}