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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '255efaf3ec0c32bba13cec148cf98013fc5b1d1b4f1b1e3caa46afde17e49f4a' 
  AND token = 'DSd0GVWlwTw6GHoOYji8k6awnZaXestYOpn4j24TNOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}