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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a45f564f52151f40e7d9240a9db4d0536b861a7d2c4da227816337ce710bad4' 
  AND token = 'cVOpvTNSWH+Ux51Ta+bZtor0mnq1lyDVGoIIKoEP9LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}