SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '369195163d78de7e2231101a2f9f983404fc0cf8abf461e5cefd75a5c00861c3' 
  AND token = 'r4APtfb/lI8Zu5D4ogx5z6rMljy9CaO0QjXN3VAWHmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}