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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b4f78cbcede0ac5dd4a9051c166c26f62c92d97f95d1f9feb12c28574f848e' 
  AND token = 'RsR91UtBFYIOyRsd2XJuQUH8oGztXhKYDLtktApWdEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}