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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d76281a8bf4f2883135ab6856f9ba113c3755566773a86c1e8c74ec3816b2a' 
  AND token = 'qJy21pAO8lgJgk4KmqqF0OQfGj2yr0CBJe6/jypQKls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}