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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435d1184b39d99e48be9cce25c877777e4ff80dea76d187d758a668a7f651636' 
  AND token = 'WP1+yLVeZp2Jp0nyRQ6R0hgAariCNoUI8ZcEQmBctS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}