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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ca02ad209e769a6e03a4dd55f7aea91574066b7ad1d540ecd930435f4b61cc' 
  AND token = 'CBSNQtUdyzvnxCV6CCkm+kGds9G++zSOyGHddaTKRxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}