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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf41a89f9e0c474881ecee6d5c8980dc56d6c59f9e03eb4e0e84f04fbcdc0a9' 
  AND token = 'mqR0C65jYm+pxIB9NQVvlnEUrHu0qBPcdVUmL4owgNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}