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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64ed921bc58b6d3a041804c807a07253c3dc052b06fac46bcc83fb7da40ddff' 
  AND token = 'TMmfHgBEWtQH3HHoHv08G5TeKHWNeS8vx3JYphU2crs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}