SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380ab68829ee1c8888bd10707b3a98ee93e6baf1702009e83dd2f3496ee5ae8a' 
  AND token = 'PukY39aBJoIyekW7Q4moc1PUBC8YlByRqqxPswW+lzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}