SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '240ca35d32e325cc495415962c932ea9ed67946a082217a74dc03ba351d1a5f0' 
  AND token = 'rwhoHn7HV7Awf9Y8Hjwh2wtHlIDLqnEZ/MVrRadf1JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}