SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18411597efcfab3fc42c64554856eb46db2cd047b6b07d3bc3d70df11dcbfb56' 
  AND token = 'tzsJAUucypdpho7nhY8evG6oNmdqoaYeG0F553lspsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}