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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c606be8165b4d339a0f8e7c94ef59723c9bdfaabed3e967b2c017f3cb3395f1' 
  AND token = 'BJf/wYa+KCMNUiTmi/Ud7cDdFYc6yzMp6h3HzEWlOf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}