SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '104e1678b3745f63094d9e64c84768c569ef3d253c859a5fafdb1da4473888d1' 
  AND token = 'HbTwOG3Seb+TeBFWaLCyDekJ9usnn3uvtNI7B3chZFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}