SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b836e06e68a2a397acba3ca384967f6430104f2c97fddbd89760337c82c21a06' 
  AND token = '++BcxnR3LRkQoQQDgW6hn1Z7ubQU2zXwm+OCl+qe/Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}