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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cabea7def77a0405c4b679b3086dce3fac7afbfcbf8cce64e323cd9225afea4' 
  AND token = 'QQvtemIqBdivSvH9MgY0EV6hjL/9NPj++n8HN/9e48E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}