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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d7c321b3da58d401e11e8f4019a8669bd95e88fe1753003e98a3d51942edb1' 
  AND token = '4TPLnAZrkXDeVQW16Tk52XwbS6ugj11fNDjJvoGeOJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}