SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e76dc7eda4656c8bb4a758dd5ca16ce3bd9bda48468339b8bd54c620325b071a' 
  AND token = '1qwOTYZ7MpkkPFID6J6cG2Uz3wZSqNPlXkrtKpeTkrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}