SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ec1e618b2ce2678bf2963b948386a727daec23b5016fc507153de7de8f8bcd' 
  AND token = 'p9lixvtMigfBjuKyN7CM5U4NmlrSDpUqQIpIJ7zld48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}