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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c67696a38b72b2a0fe85fa33bb4412ca5a39024f2206c1efd29d13096baa29b' 
  AND token = 'TQ+qhnuGKNleyfFaIrOYP697xK4o7YwSB4NMj2mk1S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}