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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e250cb5a12e327e027fa45fb309b353d639a3e4618b4a63745bf8512706f786f' 
  AND token = 'UX7J6rq1ztB8r0ibUUmy0WCkbwzZwOanYiFbYXhoVRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}