SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd76eb433e58d9ff2368375d2c35dffd41ff50f792e8d11a020550b44c95a96' 
  AND token = 'HSWJa3q1g040WBdY7gnfRFHUSSUXsWd/VJOExxx9BJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}