SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c67e67617b2319a4544bd354973b159e86b34aefa72ad3fd52896339b11c35' 
  AND token = 'E/w0+J49fO4tXO7QCx/yU82mfoGjxVxCaVIPjUAJPV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}