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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354eb894ff1645128382eb4bc77c56b2367329e1c480b8127b3c403e3df298c5' 
  AND token = 'CfiA1gnobDwah3yOkoeJtP91VwYLd6x+/cZDpJ6qXyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}