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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72b0179a4139c860d51996099bf7750b3f9d4d976e0c87771d52c8dcff4c599' 
  AND token = 'g7Xz8hkFY9rOrW1/8QIJiLA9ohtoCJfbyMrNKVE39To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}