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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35322ca0b1e9cf01c9af4c1762f5d521254410b2e0ab6f092f6703a7547bb6be' 
  AND token = 'tMSPLMgX12Elqd0vX6B157fOOtGiib7vSwWUG64vVlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}