SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c873cb015ccea311d48c7f4a99dc7bbd824e5e9958b4a5aefa40492a0f8b69d1' 
  AND token = 'U61N1Gf5VdYJpSYTEVq0H9nlV7zfIwybXz7Q0ySufYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}