SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b5d5d5fd54244096428d7ad41020fa5eb5e3fb6569d4d8bf5e521fde1f821a4' 
  AND token = 'Zw9jSFjWpeoFbsMcwFbpOx7h9YNb5HrAJ0BqvOA8lBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}