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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a50d2e311137ce4fb3344496fe3628298f828143553d7c6c62915c58f9e79a' 
  AND token = 'FYWJN626UaKO0ZK5b4TLbNIsS9IpMSVZtbk+Ldfs8bY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}