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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c665fdda0363a3d12b152df20c233e7668d3d82ecc749f03c9091b1c43620cd0' 
  AND token = 'mHLCdNK7y+LcIb+L1obomnGvLbOfjAr/DAGeiwnv2VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}