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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306d2ae152cf85b780804ec705561c306ca15dac9b4e892fbf6d945671b17fa7' 
  AND token = 'weNGxaWZnwjuGlyD4dZn8Mc8Sxc/x5zOjl4uz6rWzug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}