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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a2f8d8a0f1bdebcd946b66600a71cfd66e0bcb0e2481a2e64bcc37db0b2280' 
  AND token = 'nHo0kBOx1KjmllNJPPGGfjrkhHgTOLPiLyBmrirzcsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}