SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64ae2da0037c0ff468071d10f7e4db85fa36ca5a199bb61d23ada5e29e2edf5' 
  AND token = 'eu6Kzmdru1Vgkwz2yw1JWQi1sTnGoGjRcz55oYavrlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}