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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37eb21d7458ce33644b105a1ecc64a82e976a4027438be2cb0646323ad1dc174' 
  AND token = 'cjhBhGdPEhybgZ7gzjIaqV9Q3L0sKM5o0z8SDHfvNUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}