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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8451cfb472775b44800959da6cb6d6ee787ec6233a610d55ea344c4006b9c92' 
  AND token = 'HeTTyh3Ob8+o4ZLznJCRIwf3zPqJEL4oGcbCY1PlUvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}