SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db507f3efbd1d2f7c446995f18f2183de7b4a5e18eaf34c5f52b334bd7182c2b' 
  AND token = 'cyifibeptopDVYSKZE9VAAam6XIdEmusQIRSW3Z/zfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}